Thursday, December 29, 2005

Lost hunting for genes?

The current issue of Nature Genetics has an interesting article entitled "A road map for efficient and reliable human genome epidemiology", which champions the notion that researchers need to co-ordinate their work.

One key point the authors make is that there is still a publication bias which favours positive associations. This clear bias detracts from the scientific quality of the area as a whole, and runs the risk of engendering data dredging.

A number of online databases are also listed (many of these and more can be found here in the Links section of my web-site)...

Human Genetic Epidemiology Network (HuGENet)
(UK HuGENet Coordinating Centre)
Genetic Association Database
PharmGKB: The Pharmacogenetics and Pharmacogenomics Knowledge Base
STROBE statement


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